Modeling Ex Vivo Microwave Hyperthermia of Different Biological Tissues
Electromagnetic and thermal simulations are achieved using COMSOL Multiphysics® with 2D axisymmetrical finite–element method for a percutaneous microwave hyperthermia system with ex–vivo experiments on different biological tissues. Temperature variation and distribution are studied in the biological tissues submitted to an open ended coaxial cable as microwave applicator. Three types of heat transfer mechanism are considered: conduction, convection and surface–to–ambient radiation for interactions with the surrounding environment. For the multiphysics simulations, constant values of relative permittivity and electric conductivity are replaced by measured values of ε'(T) and σ(T) as a function of temperature in order to be as close as possible to the practical experiments. The variation of temperature in different tissues measured by an infrared sensor corresponds well with the simulated results.
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