Articles techniques et présentations

The isolation of target cells from biological samples such as serum, urine or blood in high-throughput manner without contamination with other cells is the starting point of developing effective therapy for many diseases. Currently available methods for cell isolation/separation require extra labeling. Furthermore, separating target cells using current methods do not produce pure target cell samples for further analysis. To address these issues, we proposed a label-free, low-cost and high-throughput technique based on dielectrophoresis (DEP). In dielectrophoretic cell isolation, dielectrophoretic force acting on cells produce the purity and the throughput of the cell separation. In this work, we have used the COMSOL Multiphysics® software to design electrodes and calculate the electric field gradient pattern of the electrodes.